Mutant FUS and ELAVL4 (HuD) aberrant crosstalk in Amyotrophic Lateral Sclerosis
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118347
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Determination of RNAs bound by wildtype and P525L mutant FUS in human iPSC-derived motoneurons using PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation) First, endogeneous FUS was immunoprecipitated from wildtype and FUS-P525L mutant motoneurons. Second, FUS wildtype or the P525L mutant was ectopically expressed as a flag-fusion protein and immunoprecipitated using an anti-flag antibody.
创建时间:
2024-12-06



