Canonical pathways affected in cognitively impaired youngest-old (≤86 y.o.).

†Fischer's exact test was used to calculate p-values; the ratios are between the numbers of genes from the dataset that mapped to the pathway to the total numbers of genes in the canonical pathway. MD  =  CDRs 0.5–1; SD  =  CDRs 4–5; ns- Non significant. Pathways are sorted in descending order based on significance for MD group. Common pathways between the two young-old and oldest-old dementia groups are in bold font.