HIV Integrase CORE domain in complex with 2-{2-[2-(3-{[4-(2-{[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)methyl]amino}ethyl)piperazin-1-yl]methyl}phenyl)ethynyl]-5-methyl-1-benzofuran-3-yl}acetic acid

HIV Integrase CORE domain in complex with 2-{2-[2-(3-{[4-(2-{[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)methyl]amino}ethyl)piperazin-1-yl]methyl}phenyl)ethynyl]-5-methyl-1-benzofuran-3-yl}acetic acid Descriptor: IODIDE ION, Integrase, SULFATE ION, ... Authors: Gorman, M.A, Parker, M.W. Deposit date: 2021-08-05 Release date: 2022-08-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: HIV integrase-LEDGF interaction screening by fragment linking using off-rate screening To Be Published

与2-{2-[2-(3-{[4-(2-{[(3-{2-[3-(羧甲基)-5-甲基-1-苯并呋喃-2-基]乙炔基}苯基)甲基]氨基}乙基)哌嗪-1-基]甲基}苯基)乙炔基]-5-甲基-1-苯并呋喃-3-基}乙酸结合的HIV整合酶（HIV Integrase）核心结构域复合物
描述符：碘离子（IODIDE ION）、整合酶（Integrase）、硫酸根离子（SULFATE ION）等
作者：Gorman, M.A.、Parker, M.W.
提交日期：2021-08-05
发布日期：2022-08-10
最后修改日期：2023-10-18
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.95埃（Å）
引用文献：《通过片段连接结合解离速率筛选法开展HIV整合酶-LEDGF相互作用筛选》（HIV integrase-LEDGF interaction screening by fragment linking using off-rate screening），待发表