File S1 - Cellular Changes in Blood Indicate Severe Respiratory Disease during Influenza Infections in Mice

Figures: Fig. I: The phenotypes of PR8 infected C57BL/6J (B6) and DBA/2J (D2) mice (Fig. IA) and histology of PR8M vs. PR8F infected B6 (Fig. IB) are displayed. Fig. II: Flow cytometric analyses of blood lymphocytes of PR8M and PR8F infected B6 are depicted. Fig. III+IV: Graphic representation of additional hematological red blood cell (Fig. III) and platelet related (Fig. IV) parameters determined from PR8M and PR8F infected B6 mice are provided. Fig. V: The absolute numbers of leucocytes in the lungs of PR8M and PR8F infected B6 mice were determined by flow cytometry. Tables: All hematological parameters determined are listed in Table I: B6 mice infected with 2×103FFU PR8M; Table II: B6 mice infected with 2×105FFU PR8M; Table III: B6 mice infected with 2×103FFU PR8F; Table IV: B6 mice infected with 2×103FFU hvPR8; Table V: D2 mice infected with 2×103FFU PR8M.
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