Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation
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Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation Descriptor: LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR Authors: Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. Deposit date: 2013-01-18 Release date: 2013-04-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
处于编辑构象的大肠杆菌（E. coli）亮氨酰-tRNA合成酶（leucyl-tRNA synthetase）、tRNA(Leu)574与苯并氧硼杂环（benzoxaborole）AN3017的三元复合物
描述项：亮氨酰-tRNA合成酶、镁离子、TRNALeu5 UAA同工受体
作者：Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J.
提交日期：2013-01-18
发布日期：2013-04-17
最后修改日期：2023-12-20
实验方法：X射线衍射（2.2 Å）
引用文献：《新型硼基抗革兰阴性菌抗菌剂的发现》，《Antimicrob. Agents Chemother.》，第57卷，2013年
创建时间：
2013-01-18
