Standardized incidence ratios (SIRs) for malignancies in Japan-resident Werner syndrome patients.***
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*statistically significant result (p**includes benign meningiomas diagnosed prior to 1988, but excludes non-melanoma skin neoplasms.***for patients with high WS diagnostic confidence (1965–2009).****relative to Osaka, Japan population, 1965–2009.note: analysis conditioned on a WRN pathogenic allele frequency of q = 0.0037.
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2015-12-02



