Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment.
Diffuse low-grade glioma (WHO grade II, DLGG) are infiltrative brain tumors that are generally revealed by seizures, in young patients with a normal social and professional life. In this database, we
Given that regulatory networks can be species specific, we generated two murine DMG single-cell networks by the standard application of ARACNe-AP to the normalized gene expression data from malignant
Processed mosaic of a sagittal section through the brain of mouse model of glioma. To produce transformed cells, creGFAP mice were injected in the cortex with Ras/s.i.p53 virus and perfused after 2 we