Immunoglobulins and non-categorized immune genes exhibiting differential expression between resistant and susceptible birds.
收藏Figshare2015-12-02 更新2026-04-29 收录
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Genes are ordered according to fold-difference and the direction of fold-difference is shown to indicate either increased (+) or decreased (−) expression in resistant relative to susceptible birds. The unique NCBI Gene ID for each gene is shown in the first column. All of the immunoglobulin genes, including the immunoglobulin lambda chain gene IGLL1, all four annotated immunoglobulin V-type pseudogenes and the immunoglobulin J gene (IGJ) have significantly greater expression in resistant birds. Additionally the IgM (X01613.1), IgA (S40610.1) and IgY (X07174.1) heavy chain transcripts have significantly higher expression, indicating increased IgM, IgA and IgY production. Differentially expressed genes with immunological functions which are not directly associated with lymphocyte activation or immunoglobulin production are also shown here. Innate immune genes toll-like receptor 1LA (TLR1LA) and lysozyme (LYZ) display increased expression in resistant birds whereas the proinflammatory chemokine CXCLi2 and the interferon-stimulated gene myxovirus resistance 1 (MX1) demonstrate lower expression in resistant birds.
创建时间:
2015-12-02



