Age-dependency of glucose effect on number of living rat beta cells.

Beta cells isolated from the different age groups were cultured at the indicated concentrations of glucose and the numbers of viable beta cells were determined after 15 days in culture and expressed as percent of the numbers on day 1. Data represent means ± SEM; *, p<0.05; **, p<0.01; ***, p<0.001 versus corresponding day 1 values; ≠, p<0.05; #, p<0.01 versus 8-week-old at 10 mmol/l glucose; n = 4–8.