E-MTAB-10460

NIAID Data Ecosystem2026-05-02 收录

CRISPR基因调控

RNA-seq基因表达

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Gene expression profiling (RNA-seq) experiment where CRISPRi guides were designed to target the human rs2650492 variant, the promoter of GAPDH, and a non-coding region near TUFM in HEK293t cells

创建时间：

2025-07-08

Additional file 6 of Dual CRISPR interference and activation for targeted reactivation of X-linked endogenous FOXP3 in human breast cancer cells

CRISPR基因调控

癌细胞研究

Additional file 6: Table S4. CRISPR/dCas9 DNA constructs for targeted repression of XIST and activation of FOXP3

Figshare2024-02-15 更新80

total RNA-seq from A549 (ENCSR522CJR)

肺癌细胞系转录组

RNA-seq基因表达

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

NIAID Data Ecosystem40

MYC and GATA1 CRISPRi validation sgRNAs.

CRISPR基因调控

sgRNA验证

Guide sequences are given for each target. The positive control targets a known functional sequence (e2) identified by Fulco et al. As negative controls a dCas9:KRAB only or an sgRNA targeting a non-f

NIAID Data Ecosystem30

Targeted modulation of chicken genes in vitro using CRISPRa and CRISPRi toolkit

CRISPR基因调控

基因功能研究

To investigate the effectiveness of CRISPR based gene modulation, IRF7 was repressed in dCas9-KRAB DF1 cell line or activated in dCas9-VPR DF1 cell line followed by whole transcriptome analysis Overal

NIAID Data Ecosystem50

Scaffold RNA engineering in type V CRISPR-Cas systems: a potent way to enhance gene expression in the yeast Saccharomyces cerevisiae.

CRISPR基因调控

酵母合成生物学

New, orthogonal transcription factors in eukaryotic cells have been realized by engineering nuclease-deficient CRISPR-associated proteins and/or their guide RNAs. In this work, we present a new kind o

Alliance of Genome Resources30

E-MTAB-10460

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