SNPs with cell-type-specific AEI associated with HbA1c in the Fadista data when the Segerstolpe data were used as reference.

We applied BSCET to the Fadista pancreatic islets bulk RNA-seq data [15] using the MuSiC [14] proportion estimates obtained from the Segerstolpe single-cell reference [16]. We detected 8 SNPs in 8 genes with cell-type-specific AEI significantly associated with HbA1c (FDR adjusted P-value (XLSX)