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Effects of inhibitors of CBS, guanylyl cyclase, COX and PKA on relaxations evoked by the H<sub>2</sub>S donor GYY4137 (0.1 nM–30 µM).

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Results represent the mean±s.e.m. of n preparations from 4–5 pigs. Emax is the maximal relaxation, expressed as a percentage reversal of the 0.1 µM U46619-induced contraction, obtained for each drug. pD2 = -log EC50, where EC50 is the concentration of agonist producing 50% of the Emax. Effects of inhibitors of CBS, guanylyl cyclase, COX and PKA on relaxations evoked by the H2S donor GYY4137 (0.1 nM–30 µM).

创建时间:
2014-11-21
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