FXR is required for CDCA-induced activation of the −278/+10 <i>SHP</i> promoter.
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DLD-1 cells were transfected with hFXR and hRXRα expression plasmids and various hSHP promoter constructs as indicated. Cells were treated with or without 100 µmol/L CDCA. Luciferase activity was measured to determine the SHP promoter activity. Data are presented as means ± SD; n≥3. P≤0.05 for *) in a pairwise comparison by Mann-Whitney U test.
创建时间：
2016-02-23
