Construct Design For The Crystallisation Of Huntingtin Fragments - 2018/06/11
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<strong>Project</strong> - Huntingtin structure-function open lab notebook. <strong>Objective </strong>- Use the cryo-EM structure of huntingtin in complex with HAP40 http://www.rcsb.org/structure/6EZ8 to guide construct design of discrete domains and fragments which could be amenable to successful expression and purification of monodisperse protein samples and subsequent structure solution by X-ray crystallography.
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2018-07-07
