Extrafollicular and follicular B cell activation by SARS-CoV-2

The pathway model depicts the initial B cell activation inside the lymph node and the following activation routes to differentiate to either plasmablast cells following the extrafollicular pathway or memory B cells through the follicular pathway. Detailed pathway description and its application for data visualization can be found in this preprint doi: https://doi.org/10.1101/2022.12.19.521064

通路模型描绘了淋巴细胞内初始B细胞的激活过程及其后续的激活路径，这些路径分别通过副皮质通路分化为浆细胞样细胞或通过生发中心通路分化为记忆B细胞。详细的通路描述及其在数据可视化中的应用可参见本预印本（DOI：https://doi.org/10.1101/2022.12.19.521064）。