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Genotype variants files

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DataCite Commons2025-08-12 更新2025-09-08 收录
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https://figshare.com/articles/dataset/Genotype_variants_files/29820095/1
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This folder includes genotype .vcf tables with extracted variants. The corresponding data on the whole-genome short-read sequencing are available in GenBank Sequence Read Archive (SRA) repository. They can be accessed with BioProject accession number PRJNA1230855.Biologically, the sequences were generated by BY × CEN.PK biparental (back)crossing of two <i>Saccharomyces cerevisiae</i> yeast strains. The generated haploid segregants were selected based on their tolerance to NaCl. Whole genomes of haploid segregants were sequenced; either of individual most salt tolerant winners of each generation of backcrossing procedure or pools of segregants. In the later case, the bulk of segregants was grown in two paraleles, where one was grown in reference conditions (i.e. without salt) and the other was grown in extreme salinity conditions (i.e. supplemented with NaCl). For the alignment purposes a reference <i>S. cerevisiae</i> S288C genome sequence was employed. The alternative variants, i.e. originating from non-reference CEN.PK parental strain, were extracted by the HaplotypeCaller tool of the gatk 4.6. The extracted variants (SNVs, indels) are collected in the present .vcf tables.The panel includes the following sequences:CEN.PK113-7Dreference pool of segregants F1extreme pool of segregants F1winner F1winner F2bywinner F2cenpkwinner F3bywinner F3cenpkwinner F4bywinner F4cenpkwinner F5bywinner F5cenpkwinner F6bywinner F6cenpkreference pool of segregants F7byextreme pool of segregants F7byreference pool of segregants F7cenpkextreme pool of segregants F7cenpkwinner F7bywinner F7cenpk
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figshare
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2025-08-12
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