RNA-Seq of temephos resistant and susceptible Aedes aegypti from Colombia.

This studied aimed to profile the gene expression of larvae from two field populations of Ae. aegypti with differential susceptibility to temephos. The field population from Cucuta, Colombia was found to be resistant to temephos (RR50 = 8.0) whilst larvae from Bello, Colombia were classified as susceptible (RR50 = 2.6) when compared to the susceptible laboratory adapted strain New Orleans. Whole transcriptome sequencing (RNA-Seq) was conducted on the field resistant (Cucuta), field susceptible (Bello) and lab susceptible (New Orleans) populations in order to identify differential gene expression associated with the resistant phenotype.