ITK-SYK induced peripheral T-cell lymphomas induce granulocyte activation. ITK-SYK induced peripheral T-cell lymphomas induce granulocyte activation

ITK-SYK or control vector were overexpressed in Balb/c mice and ITK-SYK mice developed peripheral T-cell lymphomas within 5 weeks. CD4+ T-cells and granulocytes were harvested from the spleens of control and ITK-SYK mice and compared. Overall design: Comparison of ITK-SYK+ and control CD4+ T-cells and granulocytes