Replication data for Correlation between DNA double strand breaks and cell death radiosensitivity markers in peripheral blood lymphocytes from breast cancer patients

The data were obtained from peripheral blood samples from a cohort of 60 breast cancer patients in remission. The data included in this file have been generated with the purpose of evaluating radioinduced apoptosis and γ-H2AX phosphorylation. These two biomarkers have been described as potential biomarkers of radiotherapy toxicity. Additionally, an analysis of 27 SNPs associated with apoptosis is also included. The analysis of γ-H2AX was performed after ex vivo irradiation of lymphocytes at a dose of 2 Gy, and was analyzed after 1, 2, 4 and 24 h after irradiation. The analysis of apoptosis was carried out after irradiating the lymphocytes at 8 Gy and was analyzed after 24 and 48 hours. Both γ-H2AX and apoptosis have been analyzed by flow cytometry.