Diagnoses among the patients of this study.

PurposeTo identify risk factors for unexpected hypotony after transconjunctival sutureless vitrectomy (TSV).MethodsIn this retrospective observational study, we defined postoperative hypotony as intraocular pressure (IOP) ResultsEight-hundred and forty eyes of 748 consecutive patients who underwent 25-G or 27-G TSV were included. Postoperative hypotony occurred in 139 eyes (16.5%) and was associated with longer axial length (AL) (odds ratio [OR], 0.86; P = 0.001) and no tamponade usage (OR, 0.50; P = 0.001). Postoperative complications occurred more frequently in the hypotony group than in the non-hypotony group (51.1% vs. 11.3%, P ConclusionLonger AL and no tamponade usage influenced hypotony post-TSV. In patients with these factors, especially with AL ≥ 26 mm, surgeons may aggressively consider suturing sclerotomy to minimize hypotony-related complications.