Hyperaccurate mitochondrial translation increases cellular proteostatic capacity
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
To etsablish how changes in mitochondrial translation accuracy impact cell physiology, we generated and analyzed mutants which increase or decrease translation accuracy. Hyperaccurate mitochondrial translation activates a retrograde signaling pathway, thereby increasing cellular proteostatic capacity. On the contrary decreased translation accuracy provokes hypersensitivity to stress.
创建时间：
2023-02-28
