124 adolescent volunteers aged 11-18 were recruited for the study, with the highest prevalence in 15-16 years old. 50% of adolescents with depression were born in single-parent families or grew up und
The innovation of this study lies in its pioneering use of 16S rDNA sequencing and LC-MS untargeted metabolomics to investigate the impact of LF on the intestinal flora and hippocampal tissue metaboli
Group I metabotropic glutamate receptors (mGluRs) are distributed primarily on postsynaptic excitatory synapses and are associated with depression. It is noticeable, however, that the antidepressant-l