Supplemental Table 1. Effects of heat stress and dietary organic acid and plant botanical supplementation on clinical assessments of lactating multiparous Holstein cows.

Forty-six pregnant multiparous and lactating Holstein cows were randomly assigned to one of four treatments at enrollment: unsupplemented thermoneutral conditions (TN-Con, n = 12), heat-stress with no organic acids and pure botanicals (OA/PB) supplementation (HS-Con, n = 12), thermoneutral conditions pair-fed to HS-Con (TN-PF, n = 12), HS supplemented with OA/PB (75 mg/kg of body weight [BW]; AviPlus R; VetAgro S.p.A., Italy; HS-OAPB, n = 10). Control cows (not supplemented with OA/PB) received a matching dose of the lipid matrix.46头经产妊娠泌乳荷斯坦奶牛（Holstein cows）于入组时被随机分为4个处理组：无添加的热中性环境组（TN-Con，n=12）、未添加有机酸与纯植物提取物（organic acids and pure botanicals，OA/PB）的热应激对照组（HS-Con，n=12）、配对饲喂HS-Con组的热中性环境组（TN-PF，n=12），以及添加OA/PB的热应激组（HS-OAPB，n=10）。其中，HS-OAPB组的OA/PB添加剂量为75 mg/kg体重（body weight，BW），所用制剂为意大利VetAgro S.p.A.公司生产的AviPlus®制剂。所有未添加OA/PB的对照组奶牛均饲喂等量的脂质载体。