Association of common HLA haplotypes with IgAD.

Shown are the summary statistics describing the association of select haplotypes on the 3 independent European case-control series. Recombinant haplotypes were defined as segments of the respective extended haplotypes and result from the occurrence of a recombination event between the HLA-B and HLA-DRB1 genes. Combined P values and odds ratios were calculated as described in Methods. N, number of haplotypes; Freq, frequency; OR, odds ratio; N/A, not available. Extended haplotypes and individual recombination events are depicted in Figure 2.