Dataset from Pilot Study To Determine The Underlying Mechanisms For Infection And Colonization By Staphylococcus Aureus Of The Skin Of Atopic Dermatitis Subjects With And Without A History Of Eczema Herpeticum (ADVN MRSA 10)

Staphylococcus aureus (S.aureus) is a bacterium that causes many painful skin and soft tissue
conditions, such as scalded-skin syndrome, boils, or impetigo. Serious cases may result in
deadly complications but S.aureus can usually be treated successfully with antibiotics. There
are, however, certain strains which cannot be treated with standard antibiotics.
Methicillin-resistant staphylococcus aureus (MRSA) is one such strain.

MRSA is increasingly being seen in both hospital and community settings, making it a serious
public health issue. People with Atopic Dermatitis (AD), particularly those with a history of
Eczema Herpeticum (EH), may be at greater risk for infection by MRSA. The reason for this
higher risk is unknown but may be linked to extended treatment with staphylococcus
antibiotics in addition to the absence of certain proteins on their skin, which have immune
function. The purpose of this study is to determine the reasons for MRSA infection in AD
participants with and without a history of EH.