Diameter stenosis at follow-up according to plasma concentrations of asymmetric dimethylarginine and trimethyllysinea.

DS, Diameter Stenosis; ADMA, asymmetric dimethylarginine; TML, trimethyllysine.aNon-parametric linear quantile mixed-effects models of diameter stenosis at follow-up using Laplace distribution.bEffect estimate given as regression coefficient (95% confidence interval) and p-value for change in percentage point diameter stenosis.cThe fixed effect in this model is ADMA and DS measured at baseline while the random effect is the clustering of arterial segments within a single patient. Estimates are presented as median (95% confidence interval). Standard error is estimated using bootstrapping.dThe fixed effect in this model is TML and DS measured at baseline while the random effect is the clustering of arterial segments within a single patient. Estimates are presented as median (95% confidence interval). Standard error is estimated using bootstrapping.eThe fixed effect in this model is DS measured at baseline, follow-up time in days, presence of diabetes, randomization (folic acid/B12 vs no folic acid/B12) status at baseline, plasma TML at baseline, smoking status, age, gender, plasma ADMA at baseline, systolic blood pressure, body mass index, kidney function, apolioprotein B100 and C-reactive protein while the random effect is the clustering of arterial segments within a single patient. Standard error is estimated using bootstrapping.