Genomic and phenotypic comparisons reveal lineage-specific traits of the probiotic Saccharomyces boulardii

Supplementary Data Description (Tables S1–S13) Supplementary Tables S1–S13. Comprehensive genomic, physiological, metabolic, and functional datasets underlying the comparative analysis of Saccharomyces boulardii and S. cerevisiae strains. This supplementary dataset contains all quantitative data supporting the results presented in the manuscript, organised as follows: - Table S1. Summary of genome assembly and annotation metrics. - Table S2. Gene cluster annotation and functional characterization. - Table S3. Summary of carbohydrate-active enzyme (CAZyme) family annotations and abundance. - Table S4. Summary of enzyme-level functional annotations. - Table S5. Summary of genes within the inversion region. - Table S6. Sequence alignment of K00234 (SDH1). - Table S7. sequence alignment of K00463 (BNA2). - Table S8. sequence alignment of K00838 (ARO8). - Table S9. multiple sequence alignment of K01568 (PDC1). - Table S10. multiple sequence alignment of K0128 (ALD6). - Table S11. sequence alignment of K0128 (ALD5). - Table S12. Summary of isolate-specific single-nucleotide variants identified among S. boulardii isolates. - Table S13. Summary of probiotic-relevant activities across all eight yeast strains.补充数据说明（表格S1至S13） 表格S1至S13：支撑布拉氏酵母菌（Saccharomyces boulardii）与酿酒酵母（Saccharomyces cerevisiae）菌株比较分析的全套基因组、生理、代谢及功能数据集。 本补充数据集包含支撑本文手稿中所有研究结果的定量数据，具体编排如下： - 表格S1：基因组组装与注释统计量汇总。 - 表格S2：基因簇注释与功能表征。 - 表格S3：碳水化合物活性酶（CAZyme）家族注释及丰度汇总。 - 表格S4：酶水平功能注释汇总。 - 表格S5：倒位区域内基因汇总。 - 表格S6：K00234（SDH1）的序列比对。 - 表格S7：K00463（BNA2）的序列比对。 - 表格S8：K00838（ARO8）的序列比对。 - 表格S9：K01568（PDC1）的多序列比对。 - 表格S10：K0128（ALD6）的多序列比对。 - 表格S11：K0128（ALD5）的序列比对。 - 表格S12：布拉氏酵母菌分离株中鉴定得到的分离株特异性单核苷酸变异体汇总。 - 表格S13：8株酵母菌株的益生菌相关活性汇总。