This project reveals the role of Gcn4 in methionine dependent regulation of anabolic response. Using ChIP seq and RNA seq approaches, we identify the direct and indirect targets of Gcn4 under methioni
Crystal of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, soaked with allosteric activators AMP and Glucose 6-Phosphate Descriptor: 6-O-phosphono-alpha-D-glucopyranose,
Total RNA was obtained from 22Rv1 cells with or without EIF3F interference to perform a High-throughput sequencing Overall design: The prostate cancer cell line 22Rv1 expressing shRNA targeting EIF3F
Mitochondria are essential organelles that play a key role in energy metabolism. Transitions between glycolytic and respiring conditions induce considerable adaptations of the cellular proteome. These
FGFRs regulate PCa development and progression, but the role of the recently found FGFR-like 1 (FGFRL1) remains unclear. The data consists of gene expression profiles of mouse subcutanous xenograft tu