Histone Methyltransferase ASH1L Primes Metastases and Metabolic Reprogramming of Macrophages in the Bone Niche
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https://www.ncbi.nlm.nih.gov/sra/SRP514101
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资源简介:
ASH1L promotes cancer metastasis, we performed single-cell RNA sequencing (scRNA-seq) to investigate the impact of ASH1L on the crosstalk of invading cancer cells and immune cells in metastatic bone niches Overall design: To generate a syngeneic bone metastasis model,DX1 cells with or without ASH1L KD were injected into the tibia of 6-week-old male C57BL/6 mice. 3wk ater injection, control and ASH1L-knockout metastatic bone tumors were dissected, minced, and digested for scRNA-seq
创建时间:
2025-05-22



