Gene expression and DNA methylation prediction model weights for East Asian TWAS and MWAS analyses

This record contains two sets of prediction model weights developed for summary-statistics-based transcriptome-wide and methylome-wide association analyses in East Asian populations. The file gene_expression_prediction_model_weight.zip contains gene expression prediction model weights designed for use with SUMMIT. These models can be used to predict genetically regulated gene expression and perform transcriptome-wide association studies (TWAS). The file methylation_prediction_model_weight_EstiMeth_database.zip contains DNA methylation prediction model weights designed for use with EstiMeth. These models can be used to predict genetically regulated DNA methylation and perform methylome-wide association studies (MWAS). These resources were generated to support reproducible multi-omics association analyses of lung cancer in East Asian populations. Please cite this Zenodo record and the associated publication when using these model weights.