Streptococcus pyogenes GapN in complex with 4-hydroxypyridazine
收藏资源简介：
Streptococcus pyogenes GapN in complex with 4-hydroxypyridazine Descriptor: 4-hydroxypyridazine, GLYCEROL, NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, ... Authors: Wirsing, R, Schindelin, H. Deposit date: 2025-05-21 Release date: 2025-11-19 Last modified: 2026-02-11 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Inhibitors of GapN-dependent NADPH supply as potential lead compounds for novel therapeutics against Streptococcus pyogenes. Virulence, 17, 2026
化脓性链球菌（Streptococcus pyogenes）GapN与4-羟基哒嗪（4-hydroxypyridazine）的复合物 描述项：4-羟基哒嗪、甘油（GLYCEROL）、烟酰胺腺嘌呤二核苷酸磷酸（NADP）依赖型甘油醛-3-磷酸脱氢酶（NADP-dependent glyceraldehyde-3-phosphate dehydrogenase）等 作者：Wirsing R、Schindelin H 存档日期：2025-05-21 发布日期：2025-11-19 最后修改日期：2026-02-11 实验方法：X射线衍射（X-RAY DIFFRACTION）（分辨率1.5埃（Å）） 引用文献：《GapN依赖性NADPH供应抑制剂作为抗化脓性链球菌新型治疗候选先导化合物》，《毒力》（Virulence），第17卷，2026年
