SYK negatively regulates ITAM-mediated NK cell signaling

NIAID Data Ecosystem2026-05-02 收录

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1171962

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Spleen tyrosine kinase (SYK) and Zeta Chain Of T Cell Receptor Associated Protein Kinase 70 (ZAP70) regulation study using KHYG1 human NK cells and Jurkat T cells.

创建时间：

2024-10-12

SYK negatively regulates ITAM-mediated NK cell signaling

Spleen tyrosine kinase (SYK) and Zeta Chain Of T Cell Receptor Associated Protein Kinase 70 (ZAP70) regulation study using KHYG1 human NK cells and Jurkat T cells.

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MAIT cells regulate NK cell mediated tumor immunity (NanoString)

This study reveals the dichotomous role of MAIT cells in regulating NK cell mediated anti-tumor immunity. B6-MAITcast MR1 WT mice were treated intranasally with 50ul PBS or 233uM 5-OP-RU on days 0, 1,

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GO:0106057 (negative regulation of calcineurin-mediated signaling)

This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.

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MAIT cells regulate NK cell mediated tumor immunity (NanoString). MAIT cells regulate NK cell mediated tumor immunity (NanoString)

This study reveals the dichotomous role of MAIT cells in regulating NK cell mediated anti-tumor immunity. Overall design: B6-MAITcast MR1 WT mice were treated intranasally with 50ul PBS or 233uM 5-OP-

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MAIT cells regulate NK cell mediated tumor immunity (RNA-Seq). MAIT cells regulate NK cell mediated tumor immunity (RNA-Seq)

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