Pre-processing method comparison on Illumina HumanMethylation450 BeadChips array. Homo sapiens

This study is trying to provide guildeline on how to identify the most optimal pre-processing method for Illumina HumanMethylation450k BeadChips array on prostate cancer dataset. Overall design: In total, we have methylation profiles for 310 samples (corresponding to 202 unique samples). Out of the 202 unique samples, 71 samples were repeated twice, 14 samples repeated three times, 3 samples repeated four times.