Spatial vulnerabilities of the Escherichia coli genome to spontaneous mutations revealed with improved duplex sequencing

Figure S1. Comparison of MAE and MSE strategies.
Figure S2. Family size and error rate across all samples.
Figure S3. Features of spontaneous mutations.
Figure S4. Signatures of mutation context.
Figure S5. The spectra and fraction of mutations.
Figure S6. The correlation between mutation and gene expression of E3C.
Table S1. Summary of data sources for error rate calculation and the 15 E.coli samples sequenced in this study.
Table S2. The error rate of the 15 Tp53 duplex sequencing datasets across 12 error types.
Table S3. The mutations we obtained in the 15 samples.
Table S4 Summary of hotspot across 15 samples.