Tissue distribution of FMDV during viremic phase of infection following IOP inoculation.

Numbers represent Log10 genome copy numbers (GCN)/mg of tissue. FMDV RNA content in serum is expressed as Log10 FMDV RNA copies/µl to facilitate comparison with viral content in tissues. Bold numbers indicate that samples were positive for both FMDV RNA (qRT-PCR) and virus isolation, (+) indicates that virus isolation was positive but FMDV RNA content was below the limit of detection, (-) indicates double negative samples. Limits of detection: tissue samples = 2.52 Log10 GCN/mg, serum≤0.1 Log10 GCN/µl (corresponding to an assay detection limit of 2.68 Log10 GCN/ml of serum). Tissue distribution of FMDV during viremic phase of infection following IOP inoculation.