Microepidemiology of plasmids in Escherichia coli and Klebsiella pneumoniae with acquired extended spectrum beta-lactamase genes isolated from chronic wounds in Ghana

Little information on the microepidemiology of mobile genetic elements like plasmids harboring acquired beta-lactamase genes in Western African Ghana is available so far. In the study presented here, we screened for plasmids in 3 Escherichia coli and 4 Klebsiella pneumoniae isolates from chronically infected wounds of Ghanaian patients expressing extended spectrum beta-lactamases (ESBL) mediated by the blaCTX-M-15 gene. The bacterial isolates were subjected to combined short-read and long-read sequencing to obtain the sequences of their plasmids