RNASeq of murine choroid plexus following one (T1), three (T3) and three days of DSS treatment followed by two days of water (T5)

To evaluate, at the molecular level, potential pathways involved in changes of PVB permeability, we dissected lateral CP tissues at all time points (T0, T1, T3, or T5) and performed transcriptional profiling by deep RNA-sequencing. We used a regression model-based method for the classification of co-regulated genes based on their temporal expression profiles and the identification of differentially expressed genes (DEGs). Overall design: The experiment includes 4 groups: CTRL (n=5), T1 (n=4), T3 (n=4), T5 (n=4)