SAHA Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network
收藏NIAID Data Ecosystem2026-03-11 收录
官方服务：
资源简介：
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景：
创建时间：
2019-03-25
相关数据集
miRNA expression of lymphoma cell lines with or without HDAC inhibitor treatment
Various types of HDAC inhibitor are now planned or on going to use against non-Hodgkin’s lymphoma including CTCL. However there is a lack of molecular based evidence not only for which HDACi might be
NIAID Data Ecosystem80
Computational Exploration of Zinc Binding Groups for HDAC Inhibition
Histone deacetylases (HDACs) have emerged as important drug targets in epigenetics. The most common HDAC inhibitors use hydroxamic acids as zinc binding groups despite unfavorable pharmacokinetic prop
NIAID Data Ecosystem50
Virtual screening, molecular docking, molecular dynamics and quantum chemical studies on (2-methoxy-4-prop-2-enylphenyl) N -(2-methoxy-4-nitrophenyl) carbamate: a novel inhibitor of hepatocellular carcinoma
HDAC protein is associated with hepatocellular carcinoma. Different medicinal plants were selected for this study to analyze the inhibitory efficacy against the target protein, HDAC. Using virtual scr
NIAID Data Ecosystem10
Examination of gene expression in human breast cancer cells exposed to the HDAC inhibitor SAHA. Homo sapiens
The identification of proteins that change in response to a drug perturbation can shed light on the molecular mechanisms of the drug and its potential use in therapies. Histone deacetylases (HDACs) ar
NIAID Data Ecosystem70
Receptor-independent ectopic activity of PROLACTIN predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies
Aim: PROLACTIN (PRL), normally produced by the pituitary gland, acts through its receptor (PRL-R) to initiate a signalling cascade to the genome. PRL can also be produced by cancer cells and become on
NIAID Data Ecosystem20
