L44 mouse bodyweight, blood glucose and serum hormone data

Blood glucose, body weight and serum hormone characterisation of the L44 mouse, a model of obesity and type 2 diabetes, over 400 days. L44 mice overexpress a nonamyloidogenic and noncytotoxic variant of human amylin that contains three proline substitutions at residues 25, 28 and 29 ([^{25, 28, 29}triprolyl]human amylin or tripro-hA). This allows for the study of the chronic effects of amylin overexpression. L44 mice were studied for a period of 400 days, with weekly blood glucose and body weight measurements. Three genotypes were examined; hemizygous (HEM), homozygous (HOM) and nontransgenic littermates (NON). Tissue and serum sample collection occurred at three time points: <b>T1:</b> 100 days <b>T2:</b> diabetes onset (3 consecutive weekly measurements of blood glucose &gt; 11 mM) <b>T3: </b>400 days Here, we provide weekly blood glucose and body weight measurements, and the circulating serum hormone levels of amylin, insulin and leptin at each time point. Abbreviations: BG = blood glucose (mM) BW = body weight (g) Sample IDs with a / are pooled serum samples from two individuals, e.g., T1 HEM 1/2 is a pooled sample with an equal volume of serum from T1 HEM 1 and T1 HEM 2.