PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000245b

PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_XST00000245b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-(2-methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 1 Authors: Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. Deposit date: 2018-08-30 Release date: 2018-10-10 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.972 Å) Cite: An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018

PanDDA分析团队提交——与化合物_XST00000245b结合的蛋白酪氨酸磷酸酶1B（Protein Tyrosine Phosphatase 1B，PTP1B）晶体结构。描述项：2-氨基-2-羟甲基丙烷-1,3-二醇、5-(2-甲基-1,3-噻唑-4-基)噻吩-2-羧酸、非受体型酪氨酸蛋白磷酸酶1型。作者：Keedy, D.A、Hill, Z.B、Biel, J.T、Kang, E、Rettenmaier, T.J、Brandao-Neto, J、von Delft, F、Wells, J.A、Fraser, J.S。提交日期：2018-08-30，发布日期：2018-10-10，最后修改日期：2024-10-16。实验方法：X射线衍射（1.972埃）。引用文献：《通过多温度晶体学、片段筛选与共价锚定技术揭示PTP1B的变构网络扩展》，《Elife》，第7卷，2018年。