The bacterial reverse gene mutation test described in OECD Test Guideline 471 is the most widely used in vitro test for the detection of mutagenicity. The standard format utilises plate incorporation
Organisation for Economic Co-operation and Development100
Figure S1. Dose-response curves of revertant Salmonella Typhimurium strain TA100 colonies following treatment with AF-2 in the absence of S9 mix (a), or with 2AA in the presence of S9 mix (b). Individ
This is a laboratory-based project to identify the mutagenic capacity of oil compounds. The Hepa1c1c2 cell line is used and the endogenous Piga gene is the target DNA for mutation assessment. 5 x 10^5
