Low-Dose CT Images of Healthy Cohort

<p>This data set includes low-dose whole body CT images and tissue segmentations of thirty healthy adult research participants who underwent PET/CT imaging on the uEXPLORER total-body PET/CT system at UC Davis. Participants included in this study were healthy adults, 18 years of age or older, who were able to provide informed written consent. The participants' age, gender, weight, height, and body mass index are also provided.</p><p>Fifteen participants underwent PET/CT imaging at three timepoints during a 3-hour period (0 minutes, 90 minutes, and 180 minutes) after PET radiotracer injection, while the remaining 15 participants were imaged at six timepoints during a 12-hour period (additionally at 360 minutes, 540 minutes, and 720 minutes). The imaging timepoint is indicated in the Series Description DICOM tag, with a value of either 'dyn', '90min', '3hr', '6hr', '9hr', or '12hr', corresponding to the delay after PET tracer injection. CT images were acquired immediately before PET image acquisition. Currently, only CT images are included in the data set from either three or six timepoints. The tissue segmentations include 37 tissues consisting of 13 abdominal organs, 20 different bones, subcutaneous and visceral fat, skeletal and psoas muscle. Segmentations were automatically generated at the 90 minute timepoint for each participant using <a href="https://github.com/QIMP-Team/MOOSE">MOOSE</a>, an AI segmentation tool for whole body data. The segmentations are provided in NIFTI format and may need to be re-oriented to correctly match the CT image data in DICOM format.</p><p>The uEXPLORER CT scanner is an 80-row, 160 slice CT scanner typically used for anatomical imaging and attenuation correction for PET/CT. The CT scan obtained at 90 minutes was performed with 140 kVp and an average of 50 mAs for all subjects. At all other time-points (0 minutes, 180 minutes, etc.) the CT scan was obtained with 140 kVp and an average of 5 mAs. CT images were reconstructed into a 512x512x828 image matrix with 0.9766x0.9766x2.344 mm3 voxel size.</p><p>A key is provided along with the segmentations download in the Data Access table which details the organ values.</p>

本数据集收录了三十位健康成年研究参与者接受UC Davis大学uEXPLORER全身PET/CT系统成像的低剂量全身CT图像和组织分割。入选本研究的研究参与者均为18岁及以上的健康成年人，且能够提供知情的书面同意。参与者的年龄、性别、体重、身高和体质指数亦一并提供。其中十五位参与者在PET示踪剂注射后的3小时期间（0分钟、90分钟和180分钟）的三个时间点接受了PET/CT成像，而剩余的十五位参与者在12小时期间（额外包括360分钟、540分钟和720分钟）的六个时间点接受了成像。成像时间点由Series Description DICOM标签指示，其值为'dyn'、'90min'、'3hr'、'6hr'、'9hr'或'12hr'，对应于PET示踪剂注射后的延迟时间。CT图像在PET图像采集之前立即获取。目前，数据集中仅包含来自三个或六个时间点的CT图像。组织分割包括37种组织，包括13个腹部器官、20种不同的骨骼、皮下和内脏脂肪、骨骼肌和腰大肌。分割在90分钟时间点自动生成，每个参与者使用<a href="https://github.com/QIMP-Team/MOOSE">MOOSE</a>（一种用于全身数据的AI分割工具）进行。分割数据以NIFTI格式提供，可能需要重新定向以正确匹配DICOM格式的CT图像数据。uEXPLORER CT扫描仪是一款80排、160层的CT扫描仪，通常用于解剖成像和PET/CT的衰减校正。90分钟时的CT扫描使用140 kVp和平均50 mAs对所有受试者进行。在所有其他时间点（0分钟、180分钟等）的CT扫描使用140 kVp和平均5 mAs。CT图像被重建为512x512x828的图像矩阵，体素大小为0.9766x0.9766x2.344 mm³。与分割数据下载一同提供的Data Access表中包含了一个详细描述器官值的键。