Renal safety of biologic and systemic therapies for psoriasis: A systematic review

Psoriasis is a chronic inflammatory disease mainly driven by T-helper-17 dysregulation. Despite increasing use of biologics and nonbiologic systemic therapies for moderate-to-severe psoriasis, data remain limited regarding the renal safety of these therapies.​1​ This systematic review investigates evidence regarding the impact of biologics and conventional systemic therapies on estimated glomerular filtration rate (eGFR).