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Lewis Acid Mediated Trifluoromethylthio Lactonization/Lactamization

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Figshare2016-02-13 更新2026-04-29 收录
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A highly selective Lewis acid mediated trifluoromethylthio lactonization/lactamization of olefins is described. The reaction was proposed to proceed via a thiiranium ion intermediate, which was further attacked by the carboxylic acid or amide to generate the corresponding trifluoromethylthiolated lactone/lactam.

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2016-02-13
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