CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE

NIAID Data Ecosystem2026-05-02 收录

HIV-1逆转录酶耐药性

艾滋病药物设计

数据链接：

https://www.rcsb.org/structure/1JLB 数据链接链接失效反馈

官方服务：

资源简介：

CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE

创建时间：

2024-10-09

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design

艾滋病药物设计

整合酶抑制剂

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design Descriptor: 5-[[[2-[[(1S)-1-(4-METHOXYPHENYL)BUTYL]CARBAMOYL]PHENYL

Protein Data Bank Japan2023-12-20 更新40

HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-[1-(1-benzyl-1H-pyrazol-4-yl)-3-(3,4-dihydro-2H-1-benzopyran-6-yl)isoquinolin-4-yl](tert-butoxy)acetic acid

HIV-1整合

艾滋病药物设计

HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-[1-(1-benzyl-1H-pyrazol-4-yl)-3-(3,4-dihydro-2H-1-benzopyran-6-yl)isoquinolin-4-yl](tert-butoxy)acetic acid

NIAID Data Ecosystem20

Name and sequence of Peptide Nucleic Acid (PNA) targeted against different sites of 5′UTR HIV-1.

艾滋病药物设计

基因靶向治疗

Name and sequence of Peptide Nucleic Acid (PNA) targeted against different sites of 5′UTR HIV-1.

Figshare2015-12-02 更新10

Normalized decision matrix NM (BP Case).

艾滋病药物设计

拓扑指数分析

Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. These

Figshare2025-01-17 更新30

HIV-1 Protease WT (NL4-3) in Complex with NR02-79

HIV-1结构解析

艾滋病药物设计

HIV-1 Protease WT (NL4-3) in Complex with NR02-79 Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{(2-ethylbutyl)[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl]amino}-3-hydroxy-1-

Protein Data Bank Japan2026-01-07 更新20

CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE

资源简介：

相关数据集