Supplementary Materials for Neuroprotective potential of thinned peaches extracts obtained by pressurized liquid extraction after different drying processes

The supporting information: Table S1: Analysis of variance for TPC for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S2: Analysis of variance for AChE for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S3: Analysis of variance for LOX for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S4: Analysis of variance for ROS for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S5: PLE conditions, desirability, predicted response values at the optimum predicted by the model and experimental response values for the selected optimum (50% ethanol at 180 ??C). Table S6: Multiple response optimization. Table S7: MS1 (m/z) and RT (min) of the internal standards used. Table S8: Abundance levels of tentatively identified metabolites in thinned peach PLE extracts. Figure S1: Response surfaces for each response variable and their corresponding standardized Pareto charts: A, TPC (mg GAE/mL); B, IC50 AChE (??g/mL); C, IC50 LOX (??g/mL); D, IC50 ROS (??g/mL). Figure S2: Desirability response surface used to optimize all response variables.