N6-methyladenosine (m6A) methyltransferase METTL3 mainly mediates mRNA m6A methylation and plays important roles in various biological processes. Here we report a chromatin-based role for METTL3 in he

NIAID Data Ecosystem50

Supplemental Material for Cannon et al., 2019

表观遗传学图谱

疾病基因组学

Supplementary figures and tables pertaining to the article titled "Open chromatin profiling in adipose tissue marks genomic regions with functional roles in cardiometabolic traits"

Figshare2019-06-11 更新30

Genome-wide maps of histone modification and chromatin remodeler binding in mouse calvaria derived stromal cell line (OP9). Genome-wide maps of histone modification and chromatin remodeler binding in mouse calvaria derived stromal cell line (OP9)

表观遗传学图谱

染色质重塑调控

We have used chromatin immunoprecipitation followed by high throughput sequencing to map regions of chromatin remodeler and histone modification state. We have used this data to understand the global

NIAID Data Ecosystem50

ChIP-seq analysis of histone modifications and RNA polymerase II at 4 stages of directed cardiac differentiation of mouse embryonic stem cells. Mus musculus

先天性心脏病表观遗传学

细胞染色质调控

We interrogated the genome-wide occupancy of histone modifications and RNA polymerase II at several stages of an mouse embryonic stem cell to cardiomyocyte directed differentiation protocol. These fou

NIAID Data Ecosystem50

Genome-wide maps of chromatin state in wild-type and SetDB1 induced knockout mESCs

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