Microbiological characteristics of patients with recurrent invasive pneumococcal disease.

P, patient identification; ST, sequence type by Multi-locus sequence typing; MDR, Multi-drug resistant strain; PCV-7, 7-valent polysaccharide-protein conjugate vaccine; PCV 13, 13-valent polysaccharide-protein conjugate vaccine; PPV-23, 23-valent pneumococcal polysaccharide vaccine; CSF, cerebrospinal fluid; NA, Not available; MIC, minimal inhibitory concentration; Pen, penicillin; Ery, erythromycin; Cm, chloramphenicol; Tet, tetracycline; Ctx, Cefotaxime; Bold text, resistant strain according to MICs for Streptococcus pneumonia. EUCAST Clinical Meningeal Breakpoints.aNA, ST were not available in episodes identified only by PCR.Microbiological characteristics of patients with recurrent invasive pneumococcal disease.