Additional file 1 of Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States
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Additional file 1: Figure S1. Pre-processing pipeline for Illumina methylation data. Table S1. Comparison of enrollment characteristics of eligible participants by follow-up status. Table S2. CpG sites and CpG clusters constructed for selected genes. Table S3. Targeted Analysis: Genomic locations of CpG sites of 9 pre-selected genes included in targeted analysis. Table S4. Exploratory EWAS: CpG sites associated with time-to-progression to CIN2+ with epigenome-wide FDR <0.05 (N=336). Table S5. CpG sites included in methylation risk scores (MRS). Table S6. Sensitivity Analysis: Targeted associations between CpG site methylation for 9 genes and time-to-progression to CIN2+ over 5 years, restricted to 262 participants identifying as “non-Hispanic White” or “Black or African American” race.
提供机构:
Ladoukakis, Efthymios; Vielot, Nadja A.; Bukowski, Alexandra; Hoyo, Cathrine; Graff, Misa; Kosorok, Michael R.; Murphy, Susan K.; North, Kari E.; Nedjai, Belinda; Maguire, Rachel L.; Smith, Jennifer S.; Brewster, Wendy R.
创建时间:
2024-08-14



