Figure 2: Bactericidal of standard antibiotics

Relative OD600 (A) and CFUs/ml (B) for P. aeruginosa Xen41 with 2-fold dilutions of ciprofloxacin, ceftazidime, kanamycin, and meropenem. (A) Ciprofloxacin was significantly different above concentrations of 0.0625 μg/ml and above. Ceftazidime and meropenem were significantly different at concentrations above 0.125 μg/ml, while kanamycin was significantly different at concentrations of 8 μg/ml and above. (B) Ciprofloxacin showed a significant decrease compared to the no treatment control for CFUs/ml at all concentrations, while ceftazidime and meropenem were significantly different at 0.25 μg/ml and above. Kanamycin didn’t show any significant difference at any concentrations. Data points are represented as means using four replicates. Error is shown in ± standard deviation (SD). Statistics were performed using 2-way ANOVA, comparing antimicrobial to no treatment control. P values are: <0.0001 = ****, between 0.0001 and 0.001 = ***, between 0.001 and 0.01 = **, and between 0.01 and 0.05 = *.